Sami I. AlEissa, Koji Tamai, Faisal Konbaz, Ahmed Alturkistany, Thomas R. Blattert, Harvinder S. Chhabra, Giuseppe Costanzo, Edward J. Dohring, Frank Kandziora, Ralph Kothe, Bernardo Misaggi, Eric J. Muehlbauer, Paulo Pereira, Shanmuganathan Rajasekaran, William J. Sullivan, Eeric Truumees, Yahya Alqahtani, Hana I. Alsobayel, Joerg Franke, Marco G. A. Teli, Jeffrey C. Wang, Hazzaa M. Al-Hazzaa, Majed Nasser Alosaimi, Sigurd Berven, Marco Brayda-Bruno, Andrew M. Briggs, Jamiu O. Busari, Antonello-Valerio Caserta, Pierre Côté, Marco Crostelli, Michael G. Fehlings, Robert Gunzburg, Sami Haddadin, Joseph Ihm, Alan S. Hilibrand, Andrea Luca, Mazza Osvaldo, Tim Pigott, Dominique A. Rothenfluh, Carlo Ruosi, Louis-Rachid Salmi, Ajoy P. Shetty, Kern Singh, Alexander R. Vaccaro, David A. Wong, Mehmet Zileli & Margareta Nordin -Show fewer authors
doi : 10.1007/s00586-021-06890-5
European Spine Journal volume 30, pages2091–2101 (2021)
The Global Burden of Diseases (GBD) Studies have estimated that low back pain is one of the costliest ailments worldwide. Subsequent to GBD publications, leadership of the four largest global spine societies agreed to form SPINE20. This article introduces the concept of SPINE20, the recommendations, and the future of this global advocacy group linked to G20 annual summits.
Harry M. Lightsey IV, Caleb M. Yeung, Dino Samartzis & Melvin C. Makhni
doi : 10.1007/s00586-021-06921-1
European Spine Journal volume 30, pages2102–2108 (2021)
Remote patient monitoring (RPM) has revolutionized the landscape of healthcare. From humble beginnings rooted in landline home telephone calls to present-day devices with near instantaneous wireless connectivity, the evolution of technology has ushered in an era of digital medicine and remote care. Presently, a vast array of healthcare data points can be automatically generated, analyzed, and forwarded to providers to supplement clinical decision-making. While RPM originated and was popularized within medicine, its role in orthopedics, and particularly within spine surgery, is evolving. We sought to provide an overview of RPM within orthopedics, with specific attention on spine care, analyzing its origins, present-day form, and prospects.
Francis Lovecchio, Grant J. Riew, Dino Samartzis, Philip K. Louie, Niccole Germscheid, Howard S. An, Jason Pui Yin Cheung, Norman Chutkan, Gary Michael Mallow, Marko H. Neva, Frank M. Phillips, Daniel M. Sciubba, Mohammad El-Sharkawi, Marcelo Valacco, Michael H. McCarthy, Melvin C. Makhni & Sravisht Iyer
doi : 10.1007/s00586-020-06653-8
European Spine Journal volume 30, pages2109–2123 (2021)
To utilize data from a global spine surgeon survey to elucidate (1) overall confidence in the telemedicine evaluation and (2) determinants of provider confidence.
Grant J. Riew, Francis Lovecchio, Dino Samartzis, David N. Bernstein, Ellen Y. Underwood, Philip K. Louie, Niccole Germscheid, Howard S. An, Jason Pui Yin Cheung, Norman Chutkan, Gary Michael Mallow, Marko H. Neva, Frank M. Phillips, Daniel M. Sciubba, Mohammad El-Sharkawi, Marcelo Valacco, Michael H. McCarthy, Sravisht Iyer & Melvin C. Makhni
doi : 10.1007/s00586-020-06707-x
European Spine Journal volume 30, pages2124–2132 (2021)
While telemedicine usage has increased due to the COVID-19 pandemic, there remains little consensus about how spine surgeons perceive virtual care. The purpose of this study was to explore international perspectives of spine providers on the challenges and benefits of telemedicine.
Peter R. Swiatek, Joseph A. Weiner, Daniel J. Johnson, Philip K. Louie, Michael H. McCarthy, Garrett K. Harada, Niccole Germscheid, Jason P. Y. Cheung, Marko H. Neva, Mohammad El-Sharkawi, Marcelo Valacco, Daniel M. Sciubba, Norman B. Chutkan, Howard S. An & Dino Samartzis
doi : 10.1007/s00586-020-06714-y
European Spine Journal volume 30, pages2133–2142 (2021)
The COVID-19 pandemic forced many surgeons to adopt “virtual medicine” practices, defined as telehealth services for patient care and online platforms for continuing medical education. The purpose of this study was to assess spine surgeon reliance on virtual medicine during the pandemic and to discuss the future of virtual medicine in spine surgery.
Karim Shafi, Francis Lovecchio, Grant J. Riew, Dino Samartzis, Philip K. Louie, Niccole Germscheid, Howard S. An, Jason Pui Yin Cheung, Norman Chutkan, Gary Michael Mallow, Marko H. Neva, Frank M. Phillips, Daniel M. Sciubba, Mohammad El-Sharkawi, Marcelo Valacco, Michael H. McCarthy, Melvin C. Makhni & Sravisht Iyer
doi : 10.1007/s00586-020-06716-w
European Spine Journal volume 30, pages2143–2149 (2021)
To utilize a global survey to elucidate spine surgeons’ perspectives towards research and resident education within telemedicine.
Rami W. Eldaya, Matthew S. Parsons, Hilary L. P. Orlowski, Martin N. Reis & Aseem Sharma
doi : 10.1007/s00586-021-06793-5
European Spine Journal volume 30, pages2150–2156 (2021)
Visualization of annular fissures on MRI is becoming increasingly important but remains challenging. Our purpose was to test whether an image processing algorithm could improve detection of annular fissures.
Wesley M. Durand, Renaud Lafage, D. Kojo Hamilton, Peter G. Passias, Han Jo Kim, Themistocles Protopsaltis, Virginie Lafage, Justin S. Smith, Christopher Shaffrey, Munish Gupta, Michael P. Kelly, Eric O. Klineberg, Frank Schwab, Jeffrey L. Gum, Gregory Mundis, Robert Eastlack, Khaled Kebaish, Alex Soroceanu, Richard A. Hostin, Doug Burton, Shay Bess, Christopher Ames, Robert A. Hart, Alan H. Daniels & International Spine Study Group (ISSG)
doi : 10.1007/s00586-021-06799-z
European Spine Journal volume 30, pages2157–2166 (2021)
AI algorithms have shown promise in medical image analysis. Previous studies of ASD clusters have analyzed alignment metrics—this study sought to complement these efforts by analyzing images of sagittal anatomical spinopelvic landmarks. We hypothesized that an AI algorithm would cluster preoperative lateral radiographs into groups with distinct morphology.
Garrett K. Harada, Zakariah K. Siyaji, G. Michael Mallow, Alexander L. Hornung, Fayyazul Hassan, Bryce A. Basques, Haseeb A. Mohammed, Arash J. Sayari, Dino Samartzis & Howard S. An
doi : 10.1007/s00586-021-06866-5
European Spine Journal volume 30, pages2167–2175 (2021)
Surgical treatment of herniated lumbar intervertebral disks is a common procedure worldwide. However, recurrent herniated nucleus pulposus (re-HNP) may develop, complicating outcomes and patient management. The purpose of this study was to utilize machine-learning (ML) analytics to predict lumbar re-HNP, whereby a personalized risk prediction can be developed as a clinical tool.
André Wirries, Florian Geiger, Ahmed Hammad, Ludwig Oberkircher, Ingmar Blümcke & Samir Jabari
doi : 10.1007/s00586-020-06613-2
European Spine Journal volume 30, pages2176–2184 (2021)
Apart from patients with severe neurological deficits, it is not clear whether surgical or conservative treatment of lumbar disc herniations is superior for the individual patient. We investigated whether deep learning techniques can predict the outcome of patients with lumbar disc herniation after 6 months of treatment.
Kazuma Murata, Kenji Endo, Takato Aihara, Hidekazu Suzuki, Yasunobu Sawaji, Yuji Matsuoka, Taichiro Takamatsu, Takamitsu Konishi, Hideya Yamauchi, Hiroo Endo & Kengo Yamamoto
doi : 10.1007/s00586-021-06914-0
European Spine Journal volume 30, pages2185–2190 (2021)
Ossification of the posterior longitudinal ligament (OPLL) causes serious problems, such as myelopathy and acute spinal cord injury. The early and accurate diagnosis of OPLL would hence prevent the miserable prognoses. Plain lateral radiography is an essential method for the evaluation of OPLL. Therefore, minimizing the diagnostic errors of OPLL on radiography is crucial. Image identification based on a residual neural network (RNN) has been recognized to be potentially effective as a diagnostic strategy for orthopedic diseases; however, the accuracy of detecting OPLL using RNN has remained unclear. An RNN was trained with plain lateral cervical radiography images of 2,318 images from 672 patients (535 images from 304 patients with OPLL and 1,773 images from 368 patients of Negative). The accuracy, sensitivity, specificity, false positive rate, and false negative rate of diagnosis of the RNN were calculated. The mean accuracy, sensitivity, specificity, false positive rate, and false negative rate of the model were 98.9%, 97.0%, 99.4%, 2.2%, and 1.0%, respectively. The model achieved an overall area under the curve of 0.99 (95% confidence interval, 0.97–1.00) in which AUC in each fold estimated was 0.99, 0.99, 0.98, 0.98, and 0.99, respectively. An algorithm trained by an RNN could make binary classification of OPLL on cervical lateral X-ray images. RNN may hence be useful as a screening tool to assist physicians in identifying patients with OPLL in future setting. To achieve accurate identification of OPLL patients clinically, RNN has to be trained with other cause of myelopathy.
Katsuhisa Yamada, Ken Nagahama, Yuichiro Abe, Yoshinori Hyugaji, Masahiko Takahata & Norimasa Iwasaki
doi : 10.1007/s00586-021-06916-y
European Spine Journal volume 30, pages2191–2199 (2021)
We developed a software program that automatically extracts a three-dimensional (3D) lumbar nerve root image from magnetic resonance imaging (MRI) lumbar nerve volume data using artificial intelligence. The aim of this study is to evaluate the morphology of Kambin's triangle in three dimensions based on an actual endoscopic transforaminal surgical approach using three-dimensional (3D) computed tomography (CT)/ magnetic resonance imaging (MRI) fusion images of the lumbar spine and nerve tissue.
Carlos Sola, Gaston Camino Willhuber, Gonzalo Kido, Matias Pereira Duarte, Mariana Bendersky, Maximiliano Mereles, Matias Petracchi & Marcelo Gruenberg
doi : 10.1007/s00586-018-5547-7
European Spine Journal volume 30, pages2200–2208 (2021)
The authors describe a percutaneous technique to treat advanced degenerative disk disease in elderly patients.
Aron Lazary
doi : 10.1007/s00586-020-06568-4
European Spine Journal volume 30, pages2209–2210 (2021)
Lei Yuan, Zhongqiang Chen, Weishi Li, Chuiguo Sun, Zhongjun Liu, Xiaoguang Liu & Huishu Yuan
doi : 10.1007/s00586-020-06688-x
European Spine Journal volume 30, pages2211–2220 (2021)
To analyze the clinical and radiographic characteristics of thoracic disk disease associated with myelopathy (TDM).
Mohamed Kamal Mesregah, Michael Repajic, Kishan Patel, Carson Gardner, Sidney Roberts, Zorica Buser & Jeffrey Wang
doi : 10.1007/s00586-021-06895-0
European Spine Journal volume 30, pages2221–2230 (2021)
This study aimed to analyse the trends and patterns of IVD degeneration in different age groups at each level of the thoracic spine.
Alessandra Colombini, Fabio Galbusera, Maria Cristina Cortese, Enrico Gallazzi, Marco Vigan?, Domenico Albano, Sabina Cauci, Luca Maria Sconfienza & Marco Brayda-Bruno
doi : 10.1007/s00586-021-06719-1
European Spine Journal volume 30, pages2231–2237 (2021)
To detect the associations between the degree of the endplate (EP) lesions with the presence of risk factors, biochemical and genetic markers previously observed in low back pain (LBP) patients with EP defects in comparison with hernia/discopathy patients and healthy controls.
Magali Millecamps, Seunghwan Lee, Daniel Z. Foster & Laura S. Stone
doi : 10.1007/s00586-021-06893-2
European Spine Journal volume 30, pages2238–2246 (2021)
Investigate the long-term behavioural, histologic and radiologic consequences on the complete lumbar spine of L4/5 intervertebral disc (IVD) injury in mice and determine if increased physical activity mitigates the observed changes.
Graciosa Q. Teixeira, Zhiyao Yong, Amelie Kuhn, Jana Riegger, Raquel M. Goncalves, Michael Ruf, Uwe M. Mauer, Markus Huber-Lang, Anita Ignatius, Rolf E. Brenner & Cornelia Neidlinger-Wilke
doi : 10.1007/s00586-021-06901-5
European Spine Journal volume 30, pages2247–2256 (2021)
Formation of terminal complement complex (TCC), a downstream complement system activation product inducing inflammatory processes and cell lysis, has been identified in degenerated discs. However, it remains unclear which molecular factors regulate complement activation during disc degeneration (DD). This study investigated a possible involvement of the pro-inflammatory cytokine interleukin-1? (IL-1?) and the lysosomal protease cathepsin D (CTSD).
Ziwei Gao, Xun Sun, Chao Chen, Zhaowei Teng, Baoshan Xu, Xinlong Ma, Zheng Wang & Qiang Yang
doi : 10.1007/s00586-021-06864-7
European Spine Journal volume 30, pages2257–2270 (2021)
To compare the outcomes of sacropelvic fixation (SPF) using sacral-2-alar iliac (S2AI) screw with SPF using iliac screw (IS).
Ram Haddas, Varun Sambhariya, Thomas Kosztowski, Andrew Block & Isador Lieberman
doi : 10.1007/s00586-020-06678-z
European Spine Journal volume 30, pages2271–2282 (2021)
To determine a classification system for cone of economy (CoE) measurements that defines clinically significant changes in altered balance and to assess if the CoE measurements directly impacts patients reported outcome measures (PROMs).
Hans-Joachim Riesner, Thomas R. Blattert, Renate Krezdorn, Simone Sch?dler & Hans-Joachim Wilke
doi : 10.1007/s00586-020-06676-1
European Spine Journal volume 30, pages2283–2291 (2021)
In an osteoporotic vertebral body, cement-augmented pedicle screw fixation could possibly be optimized by the creation of an initial cavity. The aim of this study is to compare three test groups with regard to their loosening characteristics under cyclic loading.
José M. Spirig, Elin Winkler, Frédéric Cornaz, Marie-Rosa Fasser, Michael Betz, Jess G. Snedeker, Jonas Widmer & Mazda Farshad
doi : 10.1007/s00586-021-06878-1
European Spine Journal volume 30, pages2292–2300 (2021)
The cortical bone trajectory (CBT) is an alternative to the traditional pedicle screw trajectory (TT) in posterior spinal instrumentation, enhancing screw contact with cortical bone and therefore increasing fixation strength. Additional to the trajectory, insertion depth (pericortical vs. bicortical placement) could be a relevant factor affecting the fixation strength. However, the potential biomechanical benefit of a bicortical placement of CBT screws is unknown. Therefore, the aim of this study was to quantify the fixation strength of pericortical- versus bicortical-CBT (pCBT versus bCBT) screws in a randomized cadaveric study.
Chao Tang, Ye Hui Liao, Qiang Tang, Fei Ma, Qing Wang & De Jun Zhong
doi : 10.1007/s00586-021-06884-3
European Spine Journal volume 30, pages2301–2310 (2021)
The purpose of this study was to investigate and determine whether there are differences in L5 pedicles morphology between isthmic and degenerative L5–S1 spondylolisthesis.
Jiaming Cui, Xingyu Guo, Zhaomin Zheng, Hui Liu, Hua Wang, Zemin Li & Jianru Wang
doi : 10.1007/s00586-021-06843-y
European Spine Journal volume 30, pages2311–2322 (2021)
To investigate the perioperative complications of lateral anterior lumbar interbody fusion (LaLIF) surgery.
Pedro Berjano, Andrea Zanirato, Francesco Langella, Andrea Redaelli, Carlotta Martini, Matteo Formica & Claudio Lamartina
doi : 10.1007/s00586-021-06888-z
European Spine Journal volume 30, pages2323–2332 (2021)
In cases of spine surgical revisions of patients affected by sagittal malalignment, the restoration of the ideal lumbar lordosis (LL) is mandatory. ALIF procedures represent a powerful and effective approach to improve the LL in case of hypolordosis. This study evaluates the feasibility of ALIF to overpower posterior lumbar instrumentation and fusion mass in revision spine surgery and secondarily to estimate complications, clinical and radiological outcomes.
Pascal R. Furrer, Sebastiano Caprara, Florian Wanivenhaus, Marco D. Burkhard, Marco Senteler & Mazda Farshad
doi : 10.1007/s00586-021-06852-x
European Spine Journal volume 30, pages2333–2341 (2021)
The present study compared patients developing ASD after L4/5 spinal fusion with a control group using a patient-specific statistical shape model (SSM) to find alignment-differences between the groups.
Wei Fan, Li-Xin Guo & Ming Zhang
doi : 10.1007/s00586-021-06856-7
European Spine Journal volume 30, pages2342–2350 (2021)
Biomechanical comparison between rigid and non-rigid posterior stabilization systems following lumbar interbody fusion has been conducted in several studies. However, most of these previous studies mainly focused on investigating biomechanics of adjacent spinal segments or spine stability. The objective of the present study was to compare biomechanical responses of the fusion devices when using different posterior instrumentations.
Amin Joukar, Ali Kiapour, Anoli Shah, Ardalan Seyed Vosoughi & Vijay K. Goel
doi : 10.1007/s00586-021-06863-8
European Spine Journal volume 30, pages2351–2359 (2021)
This study’s objective was to assess biomechanical parameters across fused and contralateral sacroiliac joints (SIJs) and implants during all spinal motions for both sexes. Various SIJ implant devices on the market are used in minimally invasive surgeries. These implants are placed across the joint using different surgical approaches. The biomechanical effects of fusion surgical techniques in males and females have not been studied.
Sabine Fischbeck, Katja Petrowski, Mirjam Renovanz, Rebecca Nesbigall, Julian Haaf & Florian Ringel
doi : 10.1007/s00586-021-06824-1
European Spine Journal volume 30, pages2360–2367 (2021)
Meeting the information needs of patients adequately is of high importance in informed consent consultations in surgery. However, information needs often remain unmet in the informed consent consultation. The aim of this study was to assess anxiety and pain in relation to the patients’ information needs fulfillment perioperatively.
Yu Yamato, Tomohiko Hasegawa, Go Yoshida, Tatsuya Yasuda, Tomohiro Banno, Shin Oe, Hideyuki Arima, Yuki Mihara, Hiroki Ushirozako, Tomohiro Yamada, Koichiro Ide, Yuh Watanabe & Yukihiro Matsuyama
doi : 10.1007/s00586-021-06879-0
European Spine Journal volume 30, pages2368–2376 (2021)
To determine the effect of planned two-stage surgery using lateral lumbar interbody fusion (LLIF) on the perioperative complication rate following corrective fusion surgery in patients with kyphoscoliosis.
Dominik Adl Amini, Ichiro Okano, Lisa Oezel, Jiaqi Zhu, Erika Chiapparelli, Jennifer Shue, Andrew A. Sama, Frank P. Cammisa, Federico P. Girardi & Alexander P. Hughes
doi : 10.1007/s00586-021-06912-2
European Spine Journal volume 30, pages2377–2384 (2021)
This study aims to compare the early subsidence rate (6–12 months) of standalone novel 3D-printed titanium (Ti) versus polyetheretherketone (PEEK) interbody cages after lateral lumbar interbody fusion (LLIF).
Jang Hun Kim, Sang Hoon Yoon, Suhk Que Park, Seung-Pil Ban & Byung-Kyu Cho
doi : 10.1007/s00586-021-06831-2
European Spine Journal volume 30, pages2385–2400 (2021)
Because of the rarity of the disease, paraspinal arteriovenous shunt (PAVS) is not well recognized, and therapeutic options remain controversial. To introduce a rare disease of PAVS and demonstrate its etiology, clinical features, treatment options, and outcomes, we presented a case report and conducted a systematic review and individual participants data (IPD) meta-analysis.
Naiwen Hu, Dongxia Liu, Na Zhao, Xia Wang, Yanyan Bai & Hongsheng Sun
doi : 10.1007/s00586-021-06892-3
European Spine Journal volume 30, pages2401–2408 (2021)
Human leukocyte antigen (HLA)-B27 plays a crucial role in the pathogenesis of AS. TNF polymorphisms have been reported to be associated with AS susceptibility, but the results of these previous studies have been inconsistent. The aim of this study was to explore whether TNF polymorphism is associated with AS susceptibility in HLA-27-positive population.
S. Quinones, M. Konschake, L. L. Aguilar, C. Simon, P. Aragones, L. M. Hern?ndez, A. Abramovic, S. R. Tubbs, Jose Bouzada, F. J. Valderrama-Canales, T. Vazquez & J. Sanudo
doi : 10.1007/s00586-021-06894-1
European Spine Journal volume 30, page2409 (2021)
Matthew T. Morris, Sandip P. Tarpada & Woojin Cho
doi : 10.1007/s00586-021-06900-6
European Spine Journal volume 30, pages2410–2411 (2021)
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